Question 1

What is CJC-1295?

Accepted Answer

CJC-1295 is a synthetic analog of GHRH, the hypothalamic releasing factor, modified at four positions to resist enzymatic degradation, including a substitution that blocks cleavage by dipeptidyl peptidase-4. Those changes extend its stability in plasma relative to the native sequence, which is why it appears in experimental work examining GHRH receptor signaling over longer time courses. It is frequently paired with a secretagogue such as Ipamorelin in published research designs. Prime Science Supply supplies CJC-1295 as a Research Use Only material. It is not an approved drug and is not intended for human or veterinary use.

Question 2

What is Ipamorelin?

Accepted Answer

Ipamorelin is a synthetic pentapeptide that acts as an agonist at GHS-R1a, the ghrelin receptor. Within its class it is the reference point for selectivity: earlier-generation secretagogues showed measurable cross-activity at other receptors, whereas Ipamorelin is characterized as substantially more selective, which is why it is often chosen when a clean pharmacological readout at GHS-R1a is required. Prime Science Supply supplies Ipamorelin as a Research Use Only laboratory material. It is not an approved drug and is not intended for human or veterinary use.

Question 3

Why are CJC-1295 and Ipamorelin studied together?

Accepted Answer

The two compounds act on separate receptors, which is precisely why experimental designs pair them. CJC-1295 is a GHRH analog and binds the GHRH receptor; Ipamorelin is a ghrelin receptor agonist and binds GHS-R1a. Because the two receptors sit on different signal transduction pathways, simultaneous stimulation is used in laboratory models to examine whether those pathways interact, act additively, or converge downstream. The pairing is a standard experimental configuration in somatotropic axis research, not a formulation claim. Both components are Research Use Only materials and are not intended for human or veterinary use.

Question 4

What does purity of at least 98% by HPLC-UV mean?

Accepted Answer

High-performance liquid chromatography with ultraviolet detection separates the components of a sample and measures the area under each resulting peak. A result of at least 98% purity means the peak corresponding to the target peptide accounts for at least 98% of the total detected area, indicating that truncated sequences, deletion products, and synthesis byproducts are present only in trace amounts. HPLC-UV is the standard characterization method for synthetic peptides in pharmaceutical and academic laboratories. 98% is the specification, which is a floor: the measured result for an individual lot is often higher. Where a Certificate of Analysis is issued for a lot, it reports the chromatographic result for that specific lot; CoA availability and level of detail vary by product and by lot.

Question 5

How should lyophilized peptides be stored?

Accepted Answer

Lyophilized peptide powder should be kept dry, sealed, and protected from light. Refrigeration at 2-8 °C is appropriate for short-term holding, while −20 °C or lower is used for extended storage of laboratory inventory. Moisture is the main variable to control, so a vial is best brought to ambient temperature before it is opened, preventing condensation from forming on the cold powder. Repeated freeze-thaw cycling should be avoided, since each cycle contributes to gradual degradation. Stability characteristics differ between sequences; consult the published literature for the specific peptide and any Certificate of Analysis issued for the lot.

CJC-1295 No DAC + Ipamorelin (10 mg)

ORDER MORE, SAVE MORE

Frequently asked questions about CJC-1295 No DAC + Ipamorelin (10 mg)